Difference between revisions of "ComplexNGS2025"
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| − | The seventh annual Berlin Complex Trait Analysis of Next Generation Sequence Data Course will be held at the [https://www.mdc-berlin.de/ MDC] in Berlin from September 8-12, 2025. The goal of the course is to teach both the theory and application of methods to analyze next-generation sequence (NGS) data for | + | The seventh annual Berlin Complex Trait Analysis of Next Generation Sequence Data Course will be held at the [https://www.mdc-berlin.de/ MDC] in Berlin from September 8-12, 2025. The goal of the course is to teach both the theory and application of methods to analyze next-generation sequence (NGS) data for complex human traits. Attendees will learn how to design studies, call variants from NGS data, analyze population and family-based sequence data, and evaluate variant functionality. Analyses will include performing complex trait rare variant association analysis for population and family data via linear mixed models. Exercises will be carried out using various computer programs that include ANNOVAR, LDpred2, R, and REGENIE. |
TOPICS will include sequence alignment, calling variants from NGS data, quality control of NGS data, association testing framework for quantitative and qualitative traits (fixed effects, random effects, and generalized linear mixed models and linear mixed models), rare variant association methods, polygenic risk scores, estimating power and sample size for rare variant association studies, imputation of rare variants and their analysis, and evaluating variant conservation and functionality. | TOPICS will include sequence alignment, calling variants from NGS data, quality control of NGS data, association testing framework for quantitative and qualitative traits (fixed effects, random effects, and generalized linear mixed models and linear mixed models), rare variant association methods, polygenic risk scores, estimating power and sample size for rare variant association studies, imputation of rare variants and their analysis, and evaluating variant conservation and functionality. | ||
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| − | [https://statgen.us/files/ | + | [https://statgen.us/files/2025/09/schedule_berlin_complex_ngs_2025.pdf Click here for the course schedule] |
| − | [https://statgen.us/files/ | + | [https://statgen.us/files/2025/09/Berlin_NGS_Complex_Trait_Application_2025.html Click here for the application form] |
| − | [https://statgen.us/files/ | + | [https://statgen.us/files/2025/09/Berlin_NGS_complex_traits_course_flyer_2025.pdf Click here for course flyer (please post and distribute)] |
Latest revision as of 22:50, 25 December 2024
Complex Trait Analysis of Next Generation Sequence Data Course
September 8-12, 2025
Max Delbrück Center (MDC) for Molecular Medicine
Berlin, Germany
The seventh annual Berlin Complex Trait Analysis of Next Generation Sequence Data Course will be held at the MDC in Berlin from September 8-12, 2025. The goal of the course is to teach both the theory and application of methods to analyze next-generation sequence (NGS) data for complex human traits. Attendees will learn how to design studies, call variants from NGS data, analyze population and family-based sequence data, and evaluate variant functionality. Analyses will include performing complex trait rare variant association analysis for population and family data via linear mixed models. Exercises will be carried out using various computer programs that include ANNOVAR, LDpred2, R, and REGENIE.
TOPICS will include sequence alignment, calling variants from NGS data, quality control of NGS data, association testing framework for quantitative and qualitative traits (fixed effects, random effects, and generalized linear mixed models and linear mixed models), rare variant association methods, polygenic risk scores, estimating power and sample size for rare variant association studies, imputation of rare variants and their analysis, and evaluating variant conservation and functionality.
The cost of the 5-day course is €975 for researchers from an academic institution, and €1,950 for individuals from private (for-profit) companies. This fee covers tuition, A Monday evening welcome dinner, and course-related expenses (handouts, etc.) but not room, board, or additional meals. Housing is available for course participants at nearby hotels.
The instructors for the course are Suzanne Leal (Columbia University) and Michael Nothnagel (University of Cologne).
For additional information on the Complex Trait Analysis of NGS Data Course please contact Suzanne Leal:
Email: suzannemleal@gmail.com
Click here for the course schedule
