=Genetic Association Course=
==With Application to the Analysis of Sequence and Genotype Data==
===September 5June 26-930, 20162017<br />Max Delbrück Center (MDC) for Molecular Medicine<br />Berlin, Germany===The seventh Annual eigth Annual Berlin Genetic Association Course will be held at the [http://www.mdc-berlin.de/ MDC] in Berlin from September 5June 26-930, 20162017. The goal of the course is to teach the course participants both theory and application of methods for population based association analysis, with a concentration on the analysis of exome and whole genome sequence and genotype data.
The cost of the 5 day course is 975 EUR for researchers from an academic institution, and 1,950 EUR for individuals from private (for profit) companies. This fee covers tuition, Monday evening wine and cheese party and course related expenses (handouts, etc.) but not room, board or meals. Inexpensive housing is available for course participants at the MDC and nearby hotels.
Emphasis in this course is on strategies for genetic mapping of complex human traits. It will include theory as well as practical exercises. The exercises will be carried out using a variety of computer programs (PLINK, GenABEL, MACH, UNPHASED, EIGENSTRAT, Variant Association Tools (VAT), SEQPower and R, etc.) and with pencil and paper. The emphasis of this course is analysis of population based whole genome and exome data including genotype and sequence data. TOPICS include: Association analysis of qualitative and quantitative traits; single marker and haplotype analysis; analysis of whole genome association study data; complex trait rare variant association analysis of next generation sequence data; data quality control for genotype and next generation sequence data; haplotype reconstruction; tagSNP selection; controlling population admixture (genomic genomic control, principal components analysis, etc); imputing genotype data from sequence and genotype data; detecting gene x gene and gene x environmental interactions; power and sample size estimation for both genotype and rare variant data; permutation (estimating empirical p-values); and false discovery rate (FDR). The organizers and instructors for the course are [https://www.bcm.edu/research/labs/center-for-statistical-genetics/ Suzanne Leal] (Baylor College of Medicine) and [http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/ Michael Nothnagel] (University of Cologne).
For additional information on the Genetic Association Course please contact [mailto:sleal@bcm.edu?subject=Genetic%20Association%20Course%2C%20Berlin%202015 Suzanne Leal]:
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Application Deadline May 1, 2017
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* email: [mailto:sleal@bcm.edu;suzannemleal@gmail.com?subject=Genetic%20Association%20Course%20Berlin%202016 sleal@bcm.edu]
* Tel: +1 (713) 798-4011
* Fax: +1 (713) 798-4012
=====[http://statgen.us/files/2015/09/BerlinHotelTaxExemptionForm.pdf Link to Berlin hotel tax exemption form]=====
=====[https://www.mdc-berlin.de/directions Direction to the MDC Campus]=====
=====0Direction Direction to the classroom=====
Location:
The organizers and instructors for the course are Suzanne Leal (Baylor College of Medicine) and Michael Nothnagel (University of Cologne).
[[File:20162017-09_instructors06-Instructors.jpg|none|224x300px]]
===Course Participants===
[[File:20162017-09_participants106-Participants.jpg|none|400x299px]] [[File:2016-09_participants2.jpg|none|480x203px]]
===Lecture Slides===
::* [httphttps://statgen.usresearch.bcm.edu/files/20162017/0906/auth/Berlin-lectures_2016-09coursebook_lectures.pdf Download slides here]
===Commands for Computer Exercises===
::* [[2016-genetic-association-commands|View here]]
===Exercise Files===
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/exercises.tar.gz All Exercises]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/genabel.tar.gz GenABEL]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/GWAS_part1.tar.gz GWAS Part 1]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/GWAS_part2.tar.gz GWAS Part 2]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/haplo.tar.gz haplo]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/imputation.tar.gz Imputation]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/intro.plink.R.tar.gz Intro to plink and R]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/multifactorial.tar.gz multifactorial]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/multtest.tar.gz multtest]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/pseq.tar.gz plinkSEQ]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/rvtdt.tar.gz RV-TDT]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/seqpower.tar.gz SeqPower]
::* [https://statgen.research.bcm.edu/files/2016/09/exercises/vat.tar.gz Variant Association Tools]
===Software Links===
::* [http://varianttools.sf.net/VAT Variant Association Tools]
[https://statgen.research.bcm.edu/files/2017/06/schedule_berlin_genetic_association_course_2017.pdf Click here for course schedule]
[https://statgen.research.bcm.edu/files/20162017/0906/schedule_berlin_genetic_association_course_2016Berlin_Genetic_Association_Course_Application_2017.pdf Click here for course schedule] [https://statgen.research.bcm.edu/files/2016/09/Berlin_Genetic_Association_Course_Application_2016.html htm Click here for the application form]
[https://statgen.research.bcm.edu/files/20162017/0906/Berlin_genetic_association_flyer_2016Berlin_genetic_association_flyer_2017.pdf Click here for course flyer] (please post and distribute)
[https://www.mdc-berlin.de/directions Click here for maps and directions to the MDC]<br />
[http://www.bbb-berlin.de/en/gaestehaeuser.html Click here for the information on MDC Housing]<br />
[http://www.visitberlin.de/en Click here for Berlin tourist information]<br />
[https://www.facebook.com/statgencourses/?ref=aymt_homepage_panel Click here and like us on Facebook]<br />[https://statgen.research.bcm.edu/2015SeptMDCindex.php/view Genassoc2016 Click here for photos and data from Genetic Association Course – Berlin: September 2016]<br />[https://statgen.research.bcm.edu/index.php/ComplexNGS2016 Click here for photos and datasets from Analysis of Next Generation Sequence Data for Complex Traits Course – Berlin: July 2016]<br />[https://statgen.research.bcm.edu/index.php/2015SeptMDC Click here for photos and datasets from the Analysis of Next Generation Sequence Data Mendelian Traits - Berlin: September 2015]<br />[https://statgen.research.bcm.edu/2015JuneMDCindex.php/view 2015JuneMDC Click here for photos and datasets from the Genetic Association Course - Berlin: June 2015]<br />[https://statgen.research.bcm.edu/2015MarchMDCindex.php/view 2015MarchMDC Click here for photos and datasets from the Analysis of Next Generation Sequence Data Complex Traits - Berlin: March 2015]<br />[http://portal.ccg.uni-koeln.de/ccg/researchindex.php?id=89 Click here for photos and datasets from the Genetic Association Course - Berlin: June 2015]<br /stat>[http://portal.ccg.uni-genkoeln.de/ccg/index.php?id=88 Click here for photos and datasets from the Complex Trait Analysis of NGS Data Course -bioinformaticsBerlin: March 2015]<br /courses>[http:/ngsdac2014/portal.html ccg.uni-koeln.de/ccg/index.php?id=87 Click here for photos and datasets from the Next Generation Sequence Data Analysis Course - Berlin: June 2014]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gac2014index.html php?id=86 Click here for photos and datasets from the Genetic Association Course - Berlin: March 2014]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gac2013index.html php?id=85 Click here for photos and datasets from the Genetic Association Course - Berlin: June 2013]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2012index.html php?id=84 Click here for photos and datasets from the Basic Gene Mapping Course - Berlin: November 2012]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gac2012index.html php?id=83 Click here for photos from the Genetic Association Course - Berlin: July 2012]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2011index.html php?id=81 Click here for photos from the Basic Gene Mapping Course - Berlin: November 2011]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gac2011index.html php?id=80 Click here for photos from the Genetic Association Course - Berlin: July 2011]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2010index.html php?id=63 Click here for photos from the Basic Gene Mapping Course - Berlin: October 2010]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gac2010index.html php?id=62 Click here for photos from the Genetic Association Course - Berlin: May 2010]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2009index.html php?id=90 Click here for photos from the Basic Gene Mapping Course - Berlin: November 2009]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2008index.html php?id=91 Click here for photos from the Basic Gene Mapping Course - Berlin: July 2008]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2007index.html php?id=92 Click here for photos from the Basic Gene Mapping Course - Berlin: July 2007]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2006index.html php?id=93 Click here for photos from the Basic Gene Mapping Course - Berlin: July 2006]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2005index.html php?id=94 Click here for photos from the Basic Gene Mapping Course - Berlin: July 2005]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2004index.html php?id=95 Click here for photos from the Basic Gene Mapping Course - Berlin: July 2004]<br />[http://portal.ccg.uni-koeln.de/ccg/research/stat-gen-bioinformatics/courses/gmc2003index.html php?id=96 Click here for photos from the Basic Gene Mapping Course - Berlin: July 2003]