Changes

The third fourth annual course on Complex Trait Analysis of Next Generation Sequence Data will be held at the MDC in Berlin from June 18-22, 2018. The goal of the course is to teach the course participants both the theory and application of methods to analyze next -generation sequence (NGS) data for human complex traits. Attendees will learn how to design studies, call variants from NGS data, analysis of population-, trio- and family-based sequence data and evaluation of variant functionality. Analyses will include performing complex trait rare variant association analysis for population and trio data. Exercises will be carried out using a variety of computer programs (GATK, IGV, Polyphen2, PSEQ, SEQPower, SEQSpark and Variant Association Tools (VAT)). TOPICS will be include: sequence alignment, calling variants from NGS data, quality control of NGS data, association testing framework for quantitative and qualitative traits (fixed effects, random effects and mixed models), rare variant association methods, estimating power and sample size for rare variant association studies, imputation of rare variants and their analysis, detecting putative causal variants for Mendelian traits and evaluating variant conservation and functionality.

The cost of the 5 -day course is 975 EUR for researchers from an academic institution, and 1,950 EUR for individuals from private (for profit) companies. This fee covers tuition, Monday evening wine and cheese party and course -related expenses (handouts, etc.) but not room, board or meals. Inexpensive housing is available for course participants at the MDC and nearby hotels. The maximum number of participants is 4035.

For additional information on the course please contact [mailto:sleal@bcm.edu?subject=GeneticComplex%20Association20Trait%20Analysis%20Course%20Berlin%202018 Suzanne Leal]:

email: [mailto:sleal@bcm.edu?subject=GeneticComplex%20Association20Trait%20Analysis%20Course%20Berlin%202018 sleal@bcm.edu] or [mailto:suzannemleal@gmail.com?subject=GeneticComplex%20Trait%20Association20Analysis%20Course%20Berlin%202018 suzannemleal@gmail.com]<br />

[httpshttp://statgen.research.bcm.eduus/files/2018/06/info/schedule_berlin_complex_ngs_2018.docx Click here for course schedule]<br />[httpshttp://statgen.research.bcm.eduus/files/2018/06/info/Berlin_NGS_Complex_Trait_Application_2018.htm Click here for the application form]<br />[httpshttp://statgen.research.bcm.eduus/files/2018/06/info/Berlin_NGS_complex_traits_course_flyer_2018.pdf Click here for course flyer] (please post and distribute)<br />

[httpshttp://statgen.research.bcm.eduus/index.php/Genassoc2017 Click here for photos and datasets for the Genetic Association Course – Berlin: June 2017]<br />[httpshttp://statgen.research.bcm.eduus/index.php/ComplexNGS2017 Click here for photos and datasets for Analysis of NGS data for Complex Traits Course – Berlin: March 2017]<br />[httpshttp://statgen.research.bcm.eduus/index.php/NGSMendelian2016 Click here for photos and datasets for Analysis of NGS data for Mendelian Trait Course – Berlin: October-November 2016]<br />[httpshttp://statgen.research.bcm.eduus/index.php/Genassoc2016 Click here for photos and data from Genetic Association Course – Berlin: September 2016]<br />[httpshttp://statgen.research.bcm.eduus/index.php/ComplexNGS2016 Click here for photos and datasets from Analysis of Next Generation Sequence Data for Complex Traits Course – Berlin: July 2016]<br />[httpshttp://statgen.research.bcm.eduus/index.php/2015SeptMDC Click here for photos and datasets from the Analysis of Next Generation Sequence Data Mendelian Traits - Berlin: September 2015]<br />[httpshttp://statgen.research.bcm.eduus/index.php/2015JuneMDC Click here for photos and datasets from the Genetic Association Course - Berlin: June 2015]<br />[httpshttp://statgen.research.bcm.eduus/index.php/2015MarchMDC Click here for photos and datasets from the Analysis of Next Generation Sequence Data Complex Traits - Berlin: March 2015]<br />