Advgenemap2027
From Statistical Genetics Courses
Contents
Advanced Gene Mapping Course
The Rockefeller University
Welch Building - The Great Hall
1230 York Avenue (at East 66th Street)
New York, NY 10065
Monday through Friday, January 11-15, 2027
General Information
An Advanced Gene Mapping course will be held in New York from Monday through Friday, January 11-15, 2027. The cost of the 5-day course is $200 for students, academic, and government researchers, and $3,500 for researchers working in industry. This fee covers tuition and course-related expenses.
The course emphasizes analyzing sequence and other omics data to elucidate the genetic etiology of complex human disease traits. Topics will include data quality control of sequence and other types of data; single variant and aggregate rare variant association analysis of whole-genome data (genotype, sequence, and imputed) for qualitative and quantitative traits (population and family data); controlling for population admixture and substructure; linear mixed models (LMM) and generalized LMM (GLMM); meta-analysis; sample size estimation, and power calculations; detecting gene x gene and gene x environmental interactions; heritability estimation; transcriptome-wide association studies (TWAS); analysis of RNA-Seq data; eQTL mapping; elucidating pleiotropy; functional prediction and variant annotation; estimation of polygenic risk scores; meta-analysis, Mendelian randomization; mediation analysis; LD clumping and fine mapping. As mandated by the National Institutes of Health (NIH) there will also be a special session on responsible conduct of research that will include sessions on conflict of interest, research ethics, data management (security), and ethical use of human research subjects.
A variety of freely available software will be used to perform the practical exercises, due to differences in their functionality. This software includes, but is not limited to FaST-LMM, GCTA-GREML, LDscore regression, TwoSampleMR, MR-PRESSO, Mediation, MultiPhen, mvSuSie, PLINK, R, REGENIE, and SuSiE.
Course Instructors
The instructors for the course are Heather Cordell (University of Newcastle), Andrew DeWan (Yale University), Suzanne Leal (The Rockefeller University & Columbia University), Shamil Sunyaev (Harvard University), and Gao Wang (Columbia University). TBN (HRP Consulting Group) will lecture on ethics and the regulation of human subject research. A special guest lecture will be given by Jurg Ott (The Rockefeller University).
Additional Information
The maximum number of participants for this course is 42.
Travel costs (i.e., plane, train, bus) as well as room and board (up to 295 USD per day) will be covered for non-industry participants whose home institution is more than 20 miles from The Rockefeller University.
Knowledge of genetic association analysis, genetic epidemiology, and/or statistical genetics is a screening criterion for the selection of participants. Please submit a copy of your CV with your application as well as a cover letter describing your expertise/experience in detail, e.g., research and training in statistical genetics or related fields. We may contact you personally to discuss your application.
The course is wheelchair accessible. All disabilities will be accommodated. Handicapped individuals are encouraged to apply.
The course is supported by generous funding from the National Human Genome Research Institute (2R25HG007511).
For additional information, contact the course organizers: Andrew DeWan and Suzanne Leal
Application Deadline: November 16, 2026
